Strain-Dependent Neurodevelopmental Abnormalities in Caspase-3-Deficient Mice

Targeted gene disruptions have revealed significant roles for caspase family members in the regulation of neuronal programmed cell death. Both caspase-3- and caspase-9-deficient mice exhibit a variably severe neurodevelopmental phenotype that may include marked ventricular zone expansion, exencephal...

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