Gene therapy clinical trials worldwide 1989-2004-an overview

In 1989, Rosenberg et al. performed the first human gene therapy trial when they used a retrovirus to introduce the gene coding for resistance to neomycin into human tumor‐infiltrating lymphocytes before infusing them into five patients with advanced melanoma. This study demonstrated the feasibility...

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Veröffentlicht in:	The journal of gene medicine 2004-06, Vol.6 (6), p.597-602
Hauptverfasser:	Edelstein, Michael L., Abedi, Mohammad R., Wixon, Jo, Edelstein, Richard M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenovirus Cardiovascular Diseases - genetics Cardiovascular Diseases - therapy clinical trials Clinical Trials as Topic - statistics & numerical data Clinical Trials as Topic - trends Enzymes - genetics Gene therapy Genes, Tumor Suppressor Genetic Diseases, Inborn - genetics Genetic Diseases, Inborn - therapy Genetic Therapy - methods Genetic Vectors - genetics Humans Immunotherapy - methods Neoplasms - genetics Neoplasms - therapy Prodrugs
Online-Zugang:	Volltext
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