Optimal low-density lipoprotein is 50 to 70 mg/dl: Lower is better and physiologically normal

The normal low-density lipoprotein (LDL) cholesterol range is 50 to 70 mg/dl for native hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals (all of whom do not develop atherosclerosis). Randomized trial data suggest atherosclerosis progression and coronary heart di...

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Veröffentlicht in:	Journal of the American College of Cardiology 2004-06, Vol.43 (11), p.2142-2146
Hauptverfasser:	O'Keefe, James H, Cordain, Loren, Harris, William H, Moe, Richard M, Vogel, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticholesteremic Agents - administration & dosage Atherosclerosis Biological and medical sciences Biology Cardiology Cardiology. Vascular system Cardiovascular disease Cholesterol Cholesterol - blood Cholesterol, LDL - blood Chronic illnesses Coronary Artery Disease - blood Coronary Artery Disease - prevention & control Humans Low density lipoprotein Medical sciences Mortality Practice Guidelines as Topic Randomized Controlled Trials as Topic Statins Studies Ultrasonic imaging
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Beschreibung
Zusammenfassung:	The normal low-density lipoprotein (LDL) cholesterol range is 50 to 70 mg/dl for native hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals (all of whom do not develop atherosclerosis). Randomized trial data suggest atherosclerosis progression and coronary heart disease events are minimized when LDL is lowered to
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2004.03.046