Nucleosomes Are Exposed at the Cell Surface in Apoptosis

Apoptotic cells are considered the source of DNA, histones, and nucleoprotein complexes that drive the production of autoantibodies in systemic lupus erythematosus. However, the role of apoptotic cells in the activation of the immune system is not clear. To explore interactions that may initiate or...

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Veröffentlicht in:	The Journal of immunology (1950) 2004-06, Vol.172 (11), p.6692-6700
Hauptverfasser:	Radic, Marko, Marion, Tony, Monestier, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - metabolism Apoptosis Autoantibodies - biosynthesis Cell Nucleus - immunology DNA - immunology Histones - immunology Mice Mice, Inbred BALB C Mice, Inbred NZB Nucleosomes - physiology
Online-Zugang:	Volltext
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