Krüppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells

Krüppel-like factor 6 (KLF6) is a ubiquitously expressed zinc finger transcriptional factor, which has been suggested to be a candidate tumor suppressor gene in prostate cancer and astrocytic glioma. Because KLF6 is located at chromosome 10p15, where non-small cell lung cancers (NSCLCs) also exhibit...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2004-06, Vol.64 (11), p.3838-3843
Hauptverfasser:	ITO, Genshi, UCHIYAMA, Mika, KONDO, Masashi, MORI, Shoichi, USAMI, Noriyasu, MAEDA, Osamu, KAWABE, Tsutomu, HASEGAWA, Yoshinori, SHIMOKATA, Kaoru, SEKIDO, Yoshitaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Apoptosis - genetics Biological and medical sciences Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Cell Line, Tumor Chromosomes, Human, Pair 10 - genetics Cyclin-Dependent Kinase Inhibitor p21 Cyclins - biosynthesis Cyclins - genetics Down-Regulation Female Gene Expression Regulation, Neoplastic Humans Kruppel-Like Factor 6 Kruppel-Like Transcription Factors Loss of Heterozygosity Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Medical sciences Middle Aged Mutation Pharmacology. Drug treatments Proto-Oncogene Proteins Trans-Activators - biosynthesis Trans-Activators - genetics Transfection Tumors
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