Heme Oxygenase-1 Gene Expression Modulates Angiotensin II–Induced Increase in Blood Pressure

The heme-heme oxygenase (HO) system has been implicated in the regulation of vascular reactivity and blood pressure. This study examines the notion that overexpression of HO decreases pressor responsiveness to angiotensin II (Ang II). Five-day-old Sprague-Dawley rats received an intraleft ventricula...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2004-06, Vol.43 (6), p.1221-1226
Hauptverfasser:	Yang, Liming, Quan, Shuo, Nasjletti, Alberto, Laniado-Schwartzman, Michal, Abraham, Nader G
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - antagonists & inhibitors Angiotensin II - pharmacology Animals Blood Pressure - drug effects Carbon Monoxide - physiology Heme Oxygenase (Decyclizing) - genetics Heme Oxygenase (Decyclizing) - physiology Heme Oxygenase-1 Humans Kidney - metabolism Membrane Proteins Oligonucleotides, Antisense - genetics Rats Rats, Sprague-Dawley RNA, Messenger - biosynthesis Transduction, Genetic Vasoconstriction - drug effects
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