Late results of the combined treatment with the use of preoperative chemotherapy and surgery of locally advanced non-small cell lung cancer
The aim of the study is the assessment of efficacy of combined treatment (preoperative chemotherapy and surgery) of locally advanced non-small cell lung cancer. Material included sixty-two NSCLC patients treated in the Department of Thoracic Surgery of Medical School of Lublin between February 1993...
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| Veröffentlicht in: | Pneumonologia i alergologia polska 2002, Vol.70 (1-2), p.34-43 |
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| container_title | Pneumonologia i alergologia polska |
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| creator | Furmanik, Franciszek Paprota, Krzysztof Karczmarek-Borowska, Bozena Budny, Bozena Sawicki, Marek Korobowicz, Elzbieta Zdunek, Małgorzata Jabłonka, Andrzej Jabłonka, Stanisław |
| description | The aim of the study is the assessment of efficacy of combined treatment (preoperative chemotherapy and surgery) of locally advanced non-small cell lung cancer. Material included sixty-two NSCLC patients treated in the Department of Thoracic Surgery of Medical School of Lublin between February 1993 and October 1997. Treatment was started with 2 or 3 courses of chemotherapy. In 51 cases chemotherapy was based on Cisplatin. Response (CR + PR) to chemotherapy was observed in 30 cases (48.8%). 21-25 days after last course of chemotherapy resections were carried out. In 1 case it was lobectomy, in 25 cases--pneumonectomy and in 36--extended pneumonectomy. In 56 cases resection was radical, in 6 cases non-radical. No perioperative deaths or bronchial fistulas were observed. Median survival was 21.4 months and 5-years survival--35.25%. The results confirm the usefulness of preoperative chemotherapy in locally advanced NSCLC. |
| format | Article |
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Material included sixty-two NSCLC patients treated in the Department of Thoracic Surgery of Medical School of Lublin between February 1993 and October 1997. Treatment was started with 2 or 3 courses of chemotherapy. In 51 cases chemotherapy was based on Cisplatin. Response (CR + PR) to chemotherapy was observed in 30 cases (48.8%). 21-25 days after last course of chemotherapy resections were carried out. In 1 case it was lobectomy, in 25 cases--pneumonectomy and in 36--extended pneumonectomy. In 56 cases resection was radical, in 6 cases non-radical. No perioperative deaths or bronchial fistulas were observed. Median survival was 21.4 months and 5-years survival--35.25%. 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| source | MEDLINE; DOAJ Directory of Open Access Journals |
| subjects | Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - surgery Female Humans Lung Neoplasms - drug therapy Lung Neoplasms - surgery Male Middle Aged Neoadjuvant Therapy Preoperative Care - methods Remission Induction Retrospective Studies Survival Rate Time Factors |
| title | Late results of the combined treatment with the use of preoperative chemotherapy and surgery of locally advanced non-small cell lung cancer |
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