Anaphylactic transfusion reactions in haptoglobin-deficient patients with IgE and IgG haptoglobin antibodies

BACKGROUND : Patients with haptoglobin deficiency associated with haptoglobin IgG antibodies, who experienced severe nonhemolytic transfusion reactions (NHTRs), have been identified in Japan. Haptoglobin deficiency therefore might be a risk factor for NHTRs. STUDY DESIGN AND METHODS : A total of 413...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2002-06, Vol.42 (6), p.766-773
Hauptverfasser:	Shimada, Eiko, Tadokoro, Kenji, Watanabe, Yoshihisa, Ikeda, Kazuyo, Niihara, Hiromi, Maeda, Ikiko, Isa, Kazumi, Moriya, Susumu, Ashida, Takashi, Mitsunaga, Shigeki, Nakajima, Kazunori, Juji, Takeo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Alleles Anaphylaxis - epidemiology Anaphylaxis - etiology Anaphylaxis - immunology Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antibody Specificity Arteriosclerosis Obliterans - immunology Arteriosclerosis Obliterans - therapy Basophils - immunology Basophils - metabolism Biological and medical sciences Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Blotting, Western Child Child, Preschool Comorbidity Enzyme-Linked Immunosorbent Assay Female Gene Deletion Genotype Haptoglobins - deficiency Haptoglobins - genetics Humans Hypersensitivity, Immediate - etiology Hypersensitivity, Immediate - immunology Immunization Immunodiffusion Immunoglobulin E - immunology Immunoglobulin G - immunology Infant Infant, Newborn Isoantibodies - immunology Japan - epidemiology Kidney Failure, Chronic - immunology Kidney Failure, Chronic - therapy Male Mass Screening Mast Cells - immunology Mast Cells - metabolism Medical sciences Middle Aged Myelodysplastic Syndromes - immunology Myelodysplastic Syndromes - therapy Pregnancy Pregnancy Complications - immunology Prevalence Receptors, IgE - immunology Registries Transfusion Reaction Transfusions. Complications. Transfusion reactions. Cell and gene therapy Urinary Bladder Neoplasms - immunology Urinary Bladder Neoplasms - therapy
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