Investigating antigenic variation and other parasite–host interactions in Plasmodium falciparum infections in naïve hosts

Mathematical models of the in-host dynamics of malaria infections provide a valuable tool to explore aspects of the host–parasite interaction that are not possible to investigate experimentally. This paper presents predictions of several important parameter values for 2 parasite strains/groups: para...

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Veröffentlicht in:	Parasitology 2004-04, Vol.128 (4), p.367-376
Hauptverfasser:	GATTON, M. L., CHENG, Q.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Protozoan - blood Antigenic Variation - immunology Binomial distribution Biological and medical sciences Biology Computer Simulation Erythrocytes Fixed rates Fundamental and applied biological sciences. Psychology General aspects General aspects and techniques. Study of several systematic groups. Models Host-Parasite Interactions Humans in-host dynamics Invertebrates Malaria Malaria, Falciparum - immunology mathematical modelling Mathematical models Models, Immunological Normal distribution Parasitemia - immunology Parasites Plasmodium falciparum Plasmodium falciparum - immunology Protozoan Proteins - immunology Standard deviation Stochastic Processes Vector-borne diseases
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