PKC-β controls IκB kinase lipid raft recruitment and activation in response to BCR signaling
NF-κB signaling is required for the maintenance of normal B lymphocytes, whereas dysregulated NF-κB activation contributes to B cell lymphomas. The events that regulate NF-κB signaling in B lymphocytes are poorly defined. Here, we demonstrate that PKC-β is specifically required for B cell receptor (...
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Veröffentlicht in: | Nature immunology 2002-08, Vol.3 (8), p.780-786 |
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Hauptverfasser: | , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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