Response of VEGF Expression to Amino Acid Deprivation and Inducers of Endoplasmic Reticulum Stress

Vascular endothelial growth factor (VEGF) plays an important role in initiation of the angiogenesis that leads to proliferative retinopathy. Several environmental conditions and chemical agents that influence the expression of VEGF can also cause endoplasmic reticulum (ER) stress. The hypothesis for...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2002-08, Vol.43 (8), p.2791-2798
Hauptverfasser:	Abcouwer, Steve F, Marjon, Philip L, Loper, Robyn K, Vander Jagt, David L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - deficiency Biological and medical sciences Blotting, Northern Carrier Proteins - genetics Carrier Proteins - metabolism Cell Hypoxia - physiology Cells, Cultured Endoplasmic Reticulum - physiology Endothelial Growth Factors - genetics Endothelial Growth Factors - metabolism Enzyme-Linked Immunosorbent Assay Glyceraldehyde-3-Phosphate Dehydrogenases - genetics Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism Heat-Shock Proteins Humans Lymphokines - genetics Lymphokines - metabolism Medical sciences Molecular Chaperones - genetics Molecular Chaperones - metabolism Ophthalmology Pigment Epithelium of Eye - metabolism Retinopathies RNA, Messenger - metabolism Stress, Physiological - metabolism Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors
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