Apolipoprotein E genetic polymorphism, remnant lipoproteins, and nephropathy in type 2 diabetic patients

Background: We previously showed that the apolipoprotein (apo) Eϵ2 allele is associated with the progression of diabetic nephropathy. The aim of the present study is to further investigate the association between apo E genetic polymorphism, plasma lipid levels (particularly remnant lipoproteins), an...

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Veröffentlicht in:	American journal of kidney diseases 2002-08, Vol.40 (2), p.243-251
Hauptverfasser:	Eto, Masaaki, Saito, Mieko, Okada, Mizuho, Kume, Yoshie, Kawasaki, Fumiko, Matsuda, Masafumi, Yoneda, Masaya, Matsuki, Michihiro, Takigami, Shigeru, Kaku, Kohei
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Apolipoprotein E (apo E) apolipoprotein E2 (apo E2) apolipoprotein E4 (apo E4) Apolipoproteins E - genetics Biological and medical sciences Cholesterol - blood Cross-Sectional Studies Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - genetics Diabetic Nephropathies - blood Diabetic Nephropathies - genetics diabetic nephropathy Female Gene Frequency Genotype Humans Kidneys Lipoproteins - blood Male Medical sciences mesangial cells Middle Aged Nephrology. Urinary tract diseases Polymorphism, Genetic - genetics remnant lipoproteins remnant-like lipoprotein particle (RLP) triglyceride (TG) Triglycerides - blood type 2 diabetes mellitus (DM) Urinary system involvement in other diseases. Miscellaneous
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