Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia

BACKGROUND Evidence is accumulating that several proteases are involved in prostate cancer progression. A locus which is often amplified in prostate cancer is the chromosomal region 20q13. Interestingly, one of the genes encoding the cysteine protease cathepsin X maps to this region. The aim of this...

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Veröffentlicht in:	The Prostate 2004-07, Vol.60 (2), p.109-119
Hauptverfasser:	Nägler, Dorit K., Krüger, Sabine, Kellner, Angela, Ziomek, Edmund, Menard, Robert, Buhtz, Peter, Krams, Matthias, Roessner, Albert, Kellner, Udo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Blotting, Western cathepsin Cathepsin K Cathepsins - biosynthesis Cysteine Endopeptidases - biosynthesis cysteine protease Gene Expression Profiling Gynecology. Andrology. Obstetrics Humans Immunohistochemistry In Situ Hybridization Male Male genital diseases Medical sciences Middle Aged Nephrology. Urinary tract diseases prostate carcinoma Prostatectomy Prostatic Intraepithelial Neoplasia - genetics Prostatic Intraepithelial Neoplasia - pathology Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology quantitative real-time PCR Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Tumors Tumors of the urinary system Up-Regulation Urinary tract. Prostate gland
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