Oxazolidinone: search for highly potent antibacterial

A number of substituted piperazinyl oxazolidinone derivatives have been synthesized and their antibacterial activities were evaluated. A systematic SAR was carried out to get highly potent analog of oxazolidinone. A number of substituted piperazinyl oxazolidinone derivatives have been synthesized an...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2004-06, Vol.14 (12), p.3139-3142
Hauptverfasser:	Lohray, Braj Bhushan, Lohray, Vidya Bhushan, Srivastava, Brijesh Kumar, Gupta, Sunil, Solanki, Manish, Kapadnis, Prashant, Takale, Vijay, Pandya, Purvi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - pharmacology Antibacterial Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Cinnamoyl groups Linezolid Medical sciences Microbial Sensitivity Tests - statistics & numerical data Miscellaneous Oxazolidinone Oxazolidinones - chemical synthesis Oxazolidinones - pharmacology Pharmacology. Drug treatments Structure-Activity Relationship
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