Increased Thymic Output after Initiation of Antiretroviral Therapy in Human Immunodeficiency Virus Type 1–Infected Children in the Paediatric European Network for Treatment of AIDS (PENTA) 5 Trial

To investigate the thymic contribution to immune reconstitution during antiretroviral therapy (ART), T cell receptor gene rearrangement excision circles (TRECs) were measured in peripheral blood mononuclear cells (PBMC) and CD4 cells from 33 human immunodeficiency virus (HIV) type 1–infected childre...

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Veröffentlicht in:	The Journal of infectious diseases 2002-08, Vol.186 (3), p.312-320
Hauptverfasser:	De Rossi, Anita, Walker, A. Sarah, Klein, Nigel, De Forni, Davide, King, Doug, Gibb, Diana M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Factors AIDS Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretrovirals Antiviral agents Assisted reproductive techniques B lymphocytes Biological and medical sciences Blood cells CD4-Positive T-Lymphocytes - immunology Cellular receptors Child Child, Preschool DNA, Viral - chemistry DNA, Viral - genetics Gene Rearrangement HIV HIV 1 HIV Infections - blood HIV Infections - drug therapy HIV Infections - immunology HIV-1 - genetics HIV-1 - growth & development HIV-1 - immunology Human viral diseases Humans Infant Infectious diseases Lymphocyte Subsets - immunology Major Articles Medical sciences Pharmacology. Drug treatments Receptors, Antigen, T-Cell - blood Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - immunology RNA RNA, Viral - blood T lymphocytes Thymus Gland - immunology Thymus Gland - metabolism Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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