Philadelphia chromosome‐positive mature B‐cell (Burkitt cell) leukaemia

Philadelphia chromosome‐positive (Ph+) acute leukaemia usually shows lymphoblastic morphology and a B‐precursor phenotype. The bone marrow aspirate of a 9‐year‐old boy showed a L3 blast cell morphology in 90% of cells; immunophenotyping revealed a mature B‐blast population. The translocation t(9;22)...

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Veröffentlicht in:	British journal of haematology 2002-08, Vol.118 (2), p.559-562
Hauptverfasser:	Mann, Georg, Trebo, Monika M., Haas, Oskar A., Grümayer‐Panzer, Eva R., Dworzak, Michael N., Lion, Thomas, Gadner, Helmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Combined Chemotherapy Protocols - therapeutic use Burkitt Lymphoma - drug therapy Burkitt Lymphoma - genetics Burkitt Lymphoma - pathology Burkitt's leukaemia Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - pathology Child cytogenetics Fusion Proteins, bcr-abl - genetics Gene Rearrangement, B-Lymphocyte, Light Chain Hematology Humans Immunophenotyping - methods Karyotyping - methods Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Male malignant transformation Philadelphia chromosome Translocation, Genetic
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