The ability to overcome multidrug resistance of tumor cell lines by novel acridine cytostatics with condensed heterocyclic rings

Two recently synthesized groups of acridine cytostatics containing fused heterocyclic ring(s): pyrazoloacridines (PAC) and pyrazolopyrimidoacridines (PPAC) were tested in regard to their in vitro cytotoxic activity towards a panel of sensitive and resistant human tumor cell lines. The obtained resul...

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Veröffentlicht in:	Acta biochimica polonica 2002-01, Vol.49 (1), p.87-92
Hauptverfasser:	Bontemps-Gracz, Maria M, Kupiec, Agnieszka, Antonini, Ippolito, Borowski, Edward
Format:	Artikel
Sprache:	eng
Schlagworte:	Acridines - pharmacology Drug Resistance, Multiple Humans In Vitro Techniques Pyrazoles - pharmacology Tumor Cells, Cultured - drug effects
Online-Zugang:	Volltext
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