Quantitative DNA Fingerprinting May Distinguish New Primary Breast Cancer From Disease Recurrence

Approximately 10% of women with breast cancer develop a second breast tumor, either a new primary or a recurrence. Differentiating between these entities using standard clinical and pathologic criteria remains challenging. Ambiguous cases arise, and misclassifications may occur. We investigated whet...

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Veröffentlicht in:	Journal of clinical oncology 2004-05, Vol.22 (10), p.1830-1838
Hauptverfasser:	SCHLECHTER, Benjamin L, QIONG YANG, LARSON, Pamela S, GOLUBEVA, Arina, BLANCHARD, Rita A, DE LAS MORENAS, Antonio, ROSENBERG, Carol L
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biological and medical sciences Breast Neoplasms - genetics Breast Neoplasms - pathology Case-Control Studies DNA Fingerprinting - methods Female Gynecology. Andrology. Obstetrics Humans Loss of Heterozygosity Mammary gland diseases Medical sciences Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Neoplasms, Second Primary - genetics Neoplasms, Second Primary - pathology Predictive Value of Tests Reproducibility of Results Tumors
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