Antitumor characteristics of methoxypolyethylene glycol–poly(dl-lactic acid) nanoparticles containing camptothecin

The novel nanoparticles (CPT-NP) were prepared by the solvent evaporation method using methoxypolyethylene glycol–poly(dl-lactic acid) block copolymer as a matrix and camptothecin (CPT) as an antitumor agent, and the antitumor characteristics were examined in vitro and in vivo. The mean diameter of...

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Veröffentlicht in:Journal of controlled release 2004-05, Vol.97 (1), p.101-113
Hauptverfasser: Miura, Hidetaka, Onishi, Hiraku, Sasatsu, Masanaho, Machida, Yoshiharu
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Sprache:eng
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