The case for extending storage and secretion functions of human mast cell granules to include synthesis

Ultrastructural studies using standard procedures have for years indicated close associations of ribosomes and secretory granules in human mast cells. These descriptive studies have informed new studies, using established and new ultrastructural methods based on different principles, designed to inv...

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Veröffentlicht in:	Progress in histochemistry and cytochemistry 2002, Vol.37 (3), p.231-318
Hauptverfasser:	Dvorak, Ann M., Morgan, Ellen S.
Format:	Artikel
Sprache:	eng
Schlagworte:	(hn)RNA (sn)RNAs adenine bovine serum albumin BSA cationized ferritin chondroitin sulfate colloidal gold Cytoplasmic Granules - physiology Cytoplasmic Granules - ultrastructure deoxyribonucleic acid DNA EDTA ethylene diamine tetraacetic acid granule granule associated ribosomes granule-ribosome relationship HCL heterogeneous nuclear RNA HLMCs HMCs HSA human lung mast cells human mast cell human mast cells human serum albumin Humans hydrochloric acid in situ hybridization ISH lead citrate mast cell granules Mast Cells - physiology Mast Cells - ultrastructure Microscopy, Electron NGS NHS nontraditional site normal goat serum normal human serum PBS PCFs perichromatin fibrils phosphate-buffered saline PLL poly(A) poly(U) poly-L-lysine polyadenine polyuridine polyvinyl sulfate Protein Biosynthesis protein synthesis PVS R-G rat pancreatic acinar cells RER ribonuclear proteins ribonuclease ribonuclease-gold ribonucleic acid ribosomal proteins ribosomes Ribosomes - metabolism RNA RNA - metabolism RNase RNPs rough endoplasmic reticulum RPACs secretory granules secretory-storage granules signal recognition particle small nuclear RNAs sodium chloride, sodium citrate Srp SSC synthetic granules Tris(hydroxymethyl)aminomethane hydrochloride Tris-HCl uranyl acetate uridine
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