Expression profiling using random genomic DNA microarrays identifies differentially expressed genes associated with three major developmental stages of the protozoan parasite Leishmania major

To complete its life cycle, protozoan parasites of the genus Leishmania undergo at least three major developmental transitions. However, previous efforts to identify genes showing stage regulated changes in transcript abundance have yielded relatively few. Here we used expression profiling to assess...

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Veröffentlicht in:	Molecular and biochemical parasitology 2004-07, Vol.136 (1), p.71-86
Hauptverfasser:	Akopyants, Natalia S, Matlib, Robin S, Bukanova, Elena N, Smeds, Matthew R, Brownstein, Bernard H, Stormo, Gary D, Beverley, Stephen M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Gene Expression Profiling Gene Expression Regulation Genome, Protozoan Leishmania major - genetics Leishmania major - growth & development Leishmania major - metabolism Leishmaniasis, Cutaneous - parasitology Life Cycle Stages Mice Mice, Inbred BALB C Oligonucleotide Array Sequence Analysis - methods Protozoan Proteins - genetics Protozoan Proteins - metabolism Transcription, Genetic
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