Thalassemia screening among Royal Thai Army medical cadets
Thalassemia, common in Thailand, varies from mild to severe anemia, resulting in work inefficiency, particularly during exertion. Therefore, it is important for military cadets to be screened. The objective of this study was to screen for thalassemia and hemoglobinopathies among Royal Thai Army medi...
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| Veröffentlicht in: | Military medicine 2004-04, Vol.169 (4), p.274-276 |
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| creator | Nathalang, Oytip Arnutti, Pasra Nillakupt, Kamolthip |
| description | Thalassemia, common in Thailand, varies from mild to severe anemia, resulting in work inefficiency, particularly during exertion. Therefore, it is important for military cadets to be screened. The objective of this study was to screen for thalassemia and hemoglobinopathies among Royal Thai Army medical cadets. We tested 358 third-year Royal Thai Army medical cadets for complete blood count, red blood cell indices, hemoglobin (Hb) typing, inclusion bodies, and Hb A2, and Hb E. DNA analysis confirmed alpha-thalassemia, trait detection. The Hb E trait was the most frequent, respectively, in men and women, at 12.61% and 12%, followed by the a-thalassemia1 trait, at 3.3% and 4% and the beta-trait, at 1.5% and 0%. Two cases of homozygous Hb E were found only in men. Interestingly, a mild form of 1-thalassemia/Hb E was found in one male RTA medical cadet. These findings suggest that consistent thalassemia screening should be considered. |
| doi_str_mv | 10.7205/MILMED.169.4.274 |
| format | Article |
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Therefore, it is important for military cadets to be screened. The objective of this study was to screen for thalassemia and hemoglobinopathies among Royal Thai Army medical cadets. We tested 358 third-year Royal Thai Army medical cadets for complete blood count, red blood cell indices, hemoglobin (Hb) typing, inclusion bodies, and Hb A2, and Hb E. DNA analysis confirmed alpha-thalassemia, trait detection. The Hb E trait was the most frequent, respectively, in men and women, at 12.61% and 12%, followed by the a-thalassemia1 trait, at 3.3% and 4% and the beta-trait, at 1.5% and 0%. Two cases of homozygous Hb E were found only in men. Interestingly, a mild form of 1-thalassemia/Hb E was found in one male RTA medical cadet. These findings suggest that consistent thalassemia screening should be considered.</description><identifier>ISSN: 0026-4075</identifier><identifier>EISSN: 1930-613X</identifier><identifier>DOI: 10.7205/MILMED.169.4.274</identifier><identifier>PMID: 15132228</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Anemia ; Blood diseases ; Blood tests ; Chromatography ; Female ; Genetic counseling ; Genetic Testing - methods ; Hemoglobin ; Humans ; Male ; Military Medicine - education ; Military Personnel - statistics & numerical data ; Seroepidemiologic Studies ; Students, Medical ; Thailand - epidemiology ; Thalassemia - blood ; Thalassemia - epidemiology ; Thalassemia - genetics</subject><ispartof>Military medicine, 2004-04, Vol.169 (4), p.274-276</ispartof><rights>Copyright Association of Military Surgeons of the United States Apr 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c322t-3de90acc5d5bf21253c7c7662e0ddfc2f4e950899c0ebcef1c9e837539f9c5723</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15132228$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nathalang, Oytip</creatorcontrib><creatorcontrib>Arnutti, Pasra</creatorcontrib><creatorcontrib>Nillakupt, Kamolthip</creatorcontrib><title>Thalassemia screening among Royal Thai Army medical cadets</title><title>Military medicine</title><addtitle>Mil Med</addtitle><description>Thalassemia, common in Thailand, varies from mild to severe anemia, resulting in work inefficiency, particularly during exertion. Therefore, it is important for military cadets to be screened. The objective of this study was to screen for thalassemia and hemoglobinopathies among Royal Thai Army medical cadets. We tested 358 third-year Royal Thai Army medical cadets for complete blood count, red blood cell indices, hemoglobin (Hb) typing, inclusion bodies, and Hb A2, and Hb E. DNA analysis confirmed alpha-thalassemia, trait detection. The Hb E trait was the most frequent, respectively, in men and women, at 12.61% and 12%, followed by the a-thalassemia1 trait, at 3.3% and 4% and the beta-trait, at 1.5% and 0%. Two cases of homozygous Hb E were found only in men. Interestingly, a mild form of 1-thalassemia/Hb E was found in one male RTA medical cadet. 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Therefore, it is important for military cadets to be screened. The objective of this study was to screen for thalassemia and hemoglobinopathies among Royal Thai Army medical cadets. We tested 358 third-year Royal Thai Army medical cadets for complete blood count, red blood cell indices, hemoglobin (Hb) typing, inclusion bodies, and Hb A2, and Hb E. DNA analysis confirmed alpha-thalassemia, trait detection. The Hb E trait was the most frequent, respectively, in men and women, at 12.61% and 12%, followed by the a-thalassemia1 trait, at 3.3% and 4% and the beta-trait, at 1.5% and 0%. Two cases of homozygous Hb E were found only in men. Interestingly, a mild form of 1-thalassemia/Hb E was found in one male RTA medical cadet. These findings suggest that consistent thalassemia screening should be considered.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>15132228</pmid><doi>10.7205/MILMED.169.4.274</doi><tpages>3</tpages></addata></record> |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
| subjects | Anemia Blood diseases Blood tests Chromatography Female Genetic counseling Genetic Testing - methods Hemoglobin Humans Male Military Medicine - education Military Personnel - statistics & numerical data Seroepidemiologic Studies Students, Medical Thailand - epidemiology Thalassemia - blood Thalassemia - epidemiology Thalassemia - genetics |
| title | Thalassemia screening among Royal Thai Army medical cadets |
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