Lysophospholipid G Protein-coupled Receptors
The many biological responses documented for lysophospholipids that include lysophosphatidic acid and sphingosine 1-phosphate can be mechanistically attributed to signaling through specific G protein-coupled receptors. At least nine receptors have now been identified, and the total number is likely...
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| Veröffentlicht in: | The Journal of biological chemistry 2004-05, Vol.279 (20), p.20555-20558 |
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| container_end_page | 20558 |
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| container_title | The Journal of biological chemistry |
| container_volume | 279 |
| creator | Anliker, Brigitte Chun, Jerold |
| description | The many biological responses documented for lysophospholipids that include lysophosphatidic acid and sphingosine 1-phosphate
can be mechanistically attributed to signaling through specific G protein-coupled receptors. At least nine receptors have
now been identified, and the total number is likely to be larger. In this brief review, we note cogent features of lysophospholipid
receptors, including the current nomenclature, signaling properties, development of agonists and antagonists, and physiological
functions. |
| doi_str_mv | 10.1074/jbc.R400013200 |
| format | Article |
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can be mechanistically attributed to signaling through specific G protein-coupled receptors. At least nine receptors have
now been identified, and the total number is likely to be larger. In this brief review, we note cogent features of lysophospholipid
receptors, including the current nomenclature, signaling properties, development of agonists and antagonists, and physiological
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can be mechanistically attributed to signaling through specific G protein-coupled receptors. At least nine receptors have
now been identified, and the total number is likely to be larger. In this brief review, we note cogent features of lysophospholipid
receptors, including the current nomenclature, signaling properties, development of agonists and antagonists, and physiological
functions.</description><subject>Animals</subject><subject>Fertility - genetics</subject><subject>Lysophospholipids - physiology</subject><subject>Mammals</subject><subject>Phenotype</subject><subject>Receptors, G-Protein-Coupled - genetics</subject><subject>Receptors, G-Protein-Coupled - physiology</subject><subject>Signal Transduction - physiology</subject><issn>0021-9258</issn><issn>1083-351X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMFLwzAUh4Mobk6vHmUH8WTnS9I0yVGGTmGgDAVvIU1Tm9EtNWmR_fdGNhi8x7t8v9-DD6FrDDMMPH9Yl2a2ygEAUwJwgsYYBM0ow1-naAxAcCYJEyN0EeM6UZBLfI5GmAGhUooxul_uou8aH9O2rnPVdDF9D763bpsZP3StraYra2zX-xAv0Vmt22ivDneCPp-fPuYv2fJt8Tp_XGYmB9ZnmBNjSZ4-CChry0tsmOEam5pKIFpDJUxOOBUFyzGRuqiKwgjDuax1SQWjE3S37-2C_xls7NXGRWPbVm-tH6LiWGLOOE3gbA-a4GMMtlZdcBsddgqD-vejkh919JMCN4fmodzY6ogfhCTgdg807rv5dcGq0nnT2I0iXCoCaRhj9A-OUWto</recordid><startdate>20040514</startdate><enddate>20040514</enddate><creator>Anliker, Brigitte</creator><creator>Chun, Jerold</creator><general>American Society for Biochemistry and Molecular Biology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040514</creationdate><title>Lysophospholipid G Protein-coupled Receptors</title><author>Anliker, Brigitte ; Chun, Jerold</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c405t-172ce2423980bfe7b1c5c7a1cf3902aa0d8c42738654129a6d66c8c779fab3853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Animals</topic><topic>Fertility - genetics</topic><topic>Lysophospholipids - physiology</topic><topic>Mammals</topic><topic>Phenotype</topic><topic>Receptors, G-Protein-Coupled - genetics</topic><topic>Receptors, G-Protein-Coupled - physiology</topic><topic>Signal Transduction - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Anliker, Brigitte</creatorcontrib><creatorcontrib>Chun, Jerold</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of biological chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Anliker, Brigitte</au><au>Chun, Jerold</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lysophospholipid G Protein-coupled Receptors</atitle><jtitle>The Journal of biological chemistry</jtitle><addtitle>J Biol Chem</addtitle><date>2004-05-14</date><risdate>2004</risdate><volume>279</volume><issue>20</issue><spage>20555</spage><epage>20558</epage><pages>20555-20558</pages><issn>0021-9258</issn><eissn>1083-351X</eissn><abstract>The many biological responses documented for lysophospholipids that include lysophosphatidic acid and sphingosine 1-phosphate
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now been identified, and the total number is likely to be larger. In this brief review, we note cogent features of lysophospholipid
receptors, including the current nomenclature, signaling properties, development of agonists and antagonists, and physiological
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| fulltext | fulltext |
| identifier | ISSN: 0021-9258 |
| ispartof | The Journal of biological chemistry, 2004-05, Vol.279 (20), p.20555-20558 |
| issn | 0021-9258 1083-351X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71917573 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Animals Fertility - genetics Lysophospholipids - physiology Mammals Phenotype Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - physiology Signal Transduction - physiology |
| title | Lysophospholipid G Protein-coupled Receptors |
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