D-glucose triggers multidrug resistance-associated protein (MRP)-mediated secretion of fluorescein across rat jejunum in vitro

To examine the transport characteristics of the multidrug resistance-associated protein (MRP) substrate fluorescein across the isolated rat small intestinal segments. The transport of fluorescein was studied in side-by-side diffusion chambers under short-circuited conditions at physiological pH. The...

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Veröffentlicht in:	Pharmaceutical research 2004-04, Vol.21 (4), p.635-640
Hauptverfasser:	Legen, Igor, Kristl, Albin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport - drug effects Biological Transport - physiology Fluorescein - metabolism Glucose - pharmacology Jejunum - drug effects Jejunum - metabolism Male Multidrug Resistance-Associated Proteins - physiology Rats Rats, Wistar
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