De Novo DNA Synthesis by Human DNA Polymerase λ, DNA Polymerase μ and Terminal Deoxyribonucleotidyl Transferase

DNA polymerases (pols) catalyse the synthesis of DNA. This reaction requires a primer-template DNA in order to grow from the 3′OH end of the primer along the template. On the other hand terminal deoxyribonucleotidyl transferase (TdT) catalyses the addition of nucleotides at the 3′OH end of a DNA str...

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Veröffentlicht in:	Journal of molecular biology 2004-05, Vol.339 (2), p.395-404
Hauptverfasser:	Ramadan, Kristijan, Shevelev, Igor V, Maga, Giovanni, Hübscher, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cloning, Molecular de novo DNA synthesis DNA Polymerase beta - genetics DNA Polymerase beta - metabolism DNA polymerase λ DNA polymerase μ DNA Primers DNA repair DNA Replication DNA-Directed DNA Polymerase - genetics DNA-Directed DNA Polymerase - metabolism Humans terminal deoxyribonucleotidyl transferase
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