Combinatorial informatics in the post-genomics era

Key Points A practical and cost-effective embodiment of a chemogenomics approach to drug discovery involves the following steps: Gene sequences for targets that have been identified by genomics approaches are cloned and expressed as target proteins that are suitable for screening with a probe librar...

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Veröffentlicht in:	Nature reviews. Drug discovery 2002-05, Vol.1 (5), p.337-346
Hauptverfasser:	Agrafiotis, Dimitris K., Lobanov, Victor S., Salemme, F. Raymond
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biomedical and Life Sciences Biomedicine Biotechnology Cancer Research Combinatorial analysis Combinatorial Chemistry Techniques DNA sequencing Drugs Genomics Medicinal Chemistry Methods Molecular Medicine Nucleotide sequencing Pharmacology/Toxicology Physiological aspects Product/Service Evaluations Research Design review-article
Online-Zugang:	Volltext
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