Genetic association between interleukin-10 gene promoter region polymorphisms and type 1 diabetes age-at-onset

This study investigated whether interleukin-10 (IL-10) gene promoter region polymorphisms are associated with susceptibility to or clinical presentation of type 1 diabetes. The frequency of -1082G/A, -819C/T, and -592C/A polymorphisms was analyzed in 128 Japanese patients with type 1 diabetes and in...

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Veröffentlicht in:	Human immunology 2002-08, Vol.63 (8), p.690-695
Hauptverfasser:	Ide, Akane, Kawasaki, Eiji, Abiru, Norio, Sun, Fuyan, Takahashi, Ryoko, Kuwahara, Hironaga, Fujita, Naruhiro, Kita, Atsushi, Oshima, Katsuya, Sakamaki, Hiroyuki, Uotani, Shigeo, Yamasaki, Hironori, Yamaguchi, Yoshihiko, Eguchi, Katsumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age of Onset Aged Alleles Autoantibodies - blood Case-Control Studies Child Child, Preschool Diabetes Mellitus, Type 1 - etiology Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Female Gene Frequency gene polymorphism Glutamate Decarboxylase - immunology Humans IL-10 Infant Interleukin-10 - genetics Japan Japanese Male Middle Aged onset age Polymorphism, Genetic Promoter Regions, Genetic type 1 diabetes
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