Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis

Ephrin-B/EphB family proteins are implicated in bidirectional signaling and were initially defined through the function of their ectodomain sequences in activating EphB receptor tyrosine kinases. Ephrin-B1-3 are transmembrane proteins sharing highly conserved C-terminal cytoplasmic sequences. Here w...

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Veröffentlicht in:	Journal of cell science 2002-08, Vol.115 (Pt 15), p.3073-3081
Hauptverfasser:	Huynh-Do, Uyen, Vindis, Cécile, Liu, Hua, Cerretti, Douglas Pat, McGrew, Jeffrey T, Enriquez, Miriam, Chen, Jin, Daniel, Thomas O
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence - genetics Animals Cell Adhesion - genetics Cell Membrane - metabolism Cell Movement - genetics CHO Cells Cornea - blood supply Cornea - growth & development Cornea - metabolism Cricetinae Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Ephrin-B1 - deficiency Ephrin-B1 - genetics Humans Integrins - genetics Integrins - metabolism Male MAP Kinase Signaling System - genetics Mice Mutation - genetics Neovascularization, Physiologic - genetics Organ Culture Techniques Phosphorylation Protein Structure, Tertiary - genetics Receptor, EphB1 - genetics Receptor, EphB1 - metabolism Recombinant Fusion Proteins Signal Transduction - genetics
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