Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents

The synthesis, antiviral, antifungal and anticancer activities of 4– 10 is described. The synthesis and evaluation of some 2-substituted-1,4-naphthoquinones 2, S-(1,4-naphthoquinon-2-yl)-mercaptoalkanoic acid amides 4, related benzoquinone and naphthoquinone derivatives 6– 9 and 2,3-disubstituted 1,...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2004-06, Vol.14 (11), p.2901-2904
Hauptverfasser:	Tandon, Vishnu K., Singh, Ravindra V., Yadav, Dharmendra B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Infective Agents - chemical synthesis Anti-Infective Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antineoplastic agents Antineoplastic Agents - chemical synthesis Antineoplastic Agents - pharmacology Antiviral agents Biological and medical sciences Cell Line, Tumor Cell Survival - drug effects General aspects Influenza A virus - drug effects Leukemia, Lymphoid - pathology Medical sciences Mice Microbial Sensitivity Tests Naphthoquinones - chemical synthesis Naphthoquinones - pharmacology Pharmacology. Drug treatments Simplexvirus - drug effects Structure-Activity Relationship
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