Vicilins: A case study in allergen pedigrees

The new data also extend the list of allergens that are potentially useful in immunotherapy, clinical screens, and immunoassays. [...]the data have relevance to the development of safe biotech crops, with respect to which it is essential to prevent the transfer of known or cross-reactive allergens b...

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Veröffentlicht in:Journal of allergy and clinical immunology 2002-07, Vol.110 (1), p.26-27
Hauptverfasser: Astwood, James D., Silvanovich, Andre, Bannon, Gary A.
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container_issue 1
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container_title Journal of allergy and clinical immunology
container_volume 110
creator Astwood, James D.
Silvanovich, Andre
Bannon, Gary A.
description The new data also extend the list of allergens that are potentially useful in immunotherapy, clinical screens, and immunoassays. [...]the data have relevance to the development of safe biotech crops, with respect to which it is essential to prevent the transfer of known or cross-reactive allergens between commodity crops. [...]we know that the degree of similarity between allergen and nonallergen homologs varies widely in nature. [...]there is no consensus as to what degree of sequence identity/similarity is required to or predicted to elicit clinical cross-reactivity.
doi_str_mv 10.1067/mai.2002.125690
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subjects Agricultural biotechnology
Allergens - chemistry
Allergens - classification
Allergens - immunology
Allergies
Amino acids
biotechnology
Cross Reactions
Cross-reactivity
epitope
Food
Humans
Hypersensitivity - etiology
Immunoglobulin E - metabolism
Legumes
Nuts - immunology
Plant Proteins - chemistry
Plant Proteins - classification
Plant Proteins - immunology
Plant Proteins - metabolism
Proteins
Seed Storage Proteins
Seeds
title Vicilins: A case study in allergen pedigrees
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