Bmp signaling is required for development of primary lens fiber cells

We have investigated the role of Bmp signaling in development of the mouse lens using three experimental strategies. First, we have shown that the Bmp ligand inhibitor noggin can suppress the differentiation of primary lens fiber cells in explant culture. Second, we have expressed a dominant-negativ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Development (Cambridge) 2002-08, Vol.129 (15), p.3727-3737
Hauptverfasser:	Faber, Sonya C, Robinson, Michael L, Makarenkova, Helen P, Lang, Richard A
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin Receptors, Type I - genetics Activin Receptors, Type I - metabolism Activins - metabolism Animals Bone Morphogenetic Protein Receptors, Type I Bone Morphogenetic Protein Receptors, Type II Bone Morphogenetic Proteins - antagonists & inhibitors Bone Morphogenetic Proteins - metabolism Carrier Proteins Cell Differentiation - physiology Crystallins - metabolism Culture Techniques DNA-Binding Proteins - metabolism Embryo, Mammalian - anatomy & histology Embryo, Mammalian - physiology Follistatin Genes, Reporter In Situ Hybridization Lens, Crystalline - cytology Lens, Crystalline - drug effects Lens, Crystalline - embryology Ligands Mice Mice, Transgenic Models, Biological Phenotype Protein Serine-Threonine Kinases - metabolism Proteins - pharmacology Receptors, Growth Factor Signal Transduction - physiology Smad Proteins Trans-Activators - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!