HOXB13 homeodomain protein suppresses the growth of prostate cancer cells by the negative regulation of T-cell factor 4

In prostate gland, HOXB13 is highly expressed from the embryonic stages to adulthood. However, the function of HOXB13 in normal cell growth and tumorigenesis is not yet known. We investigated the role of HOXB13 and mechanism by which it functions in HOXB13-negative cells. Expression of HOXB13 was fo...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2004-05, Vol.64 (9), p.3046-3051
Hauptverfasser:	JUNG, Chaeyong, KIM, Ran-Sook, LEE, Sang-Jin, CHIHUEI WANG, JENG, Meei-Huey
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Cell Division - physiology Cell Line, Tumor Down-Regulation Gene Expression Regulation, Neoplastic Homeodomain Proteins - biosynthesis Homeodomain Proteins - genetics Homeodomain Proteins - physiology Humans Male Medical sciences Pharmacology. Drug treatments Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology TCF Transcription Factors Transcription Factor 7-Like 2 Protein Transcription Factors - biosynthesis Transcription Factors - genetics Transcription Factors - physiology Transfection Tumors
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