BRCA1 Regulates the Interferon γ-mediated Apoptotic Response

BRCA1 is a tumor suppressor gene implicated in transcriptional regulation. We have generated cell lines with inducible expression of BRCA1 as a tool to identify downstream targets that may be important mediators of BRCA1 function. Oligonucleotide array-based expression profiling identified 11 previo...

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Veröffentlicht in:	The Journal of biological chemistry 2002-07, Vol.277 (29), p.26225-26232
Hauptverfasser:	Andrews, Heather N., Mullan, Paul B., McWilliams, Stewart, Sebelova, Sarka, Quinn, Jennifer E., Gilmore, Paula M., McCabe, Nuala, Pace, Amy, Koller, Beverly, Johnston, Patrick G., Haber, Daniel A., Harkin, D. Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Blotting, Western BRCA1 Protein - genetics Cell Line DNA-Binding Proteins - biosynthesis Gene Expression Regulation Genes, BRCA1 - physiology GTP-Binding Proteins Humans Interferon Regulatory Factor-7 Interferon-gamma - physiology Myxovirus Resistance Proteins Oligonucleotide Array Sequence Analysis Protein Biosynthesis Up-Regulation
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