Preparation of vaccines against H5N1 influenza
In response to the pandemic warning provided by the highly pathogenic H5N1 influenza virus infections in Hong Kong, there were world-wide attempts to develop vaccines. Three strategies were followed and although each was associated with some success, there were also some problems. Pre-clinical vacci...
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Veröffentlicht in: | Vaccine 2002-05, Vol.20, p.S84-S87 |
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container_title | Vaccine |
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creator | Wood, J.M Major, D Newman, R.W Dunleavy, U Nicolson, C Robertson, J.S Schild, G.C |
description | In response to the pandemic warning provided by the highly pathogenic H5N1 influenza virus infections in Hong Kong, there were world-wide attempts to develop vaccines. Three strategies were followed and although each was associated with some success, there were also some problems. Pre-clinical vaccine efficacy results are presented from one such strategy, that of using an apathogenic H5N3 avian strain for vaccine production. |
doi_str_mv | 10.1016/S0264-410X(02)00139-1 |
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Pre-clinical vaccine efficacy results are presented from one such strategy, that of using an apathogenic H5N3 avian strain for vaccine production.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/S0264-410X(02)00139-1</identifier><identifier>PMID: 12110267</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Animals ; Baculoviridae - genetics ; Humans ; Influenza A (H5N1) ; Influenza A virus - immunology ; Influenza A Virus, H5N1 Subtype ; Influenza Vaccines - immunology ; Influenza virus ; Mice ; Vaccine ; Vaccines, Attenuated - immunology ; Vaccines, Synthetic - immunology ; Virus</subject><ispartof>Vaccine, 2002-05, Vol.20, p.S84-S87</ispartof><rights>2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c524t-29ebeea503c4cc6c2ef4772bf55620c0d28b5dbd4209caaff2a37721239931fe3</citedby><cites>FETCH-LOGICAL-c524t-29ebeea503c4cc6c2ef4772bf55620c0d28b5dbd4209caaff2a37721239931fe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0264410X02001391$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12110267$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kitler, ME</contributor><contributor>Lavanchy, D</contributor><contributor>Osterhaus, ADME</contributor><creatorcontrib>Wood, J.M</creatorcontrib><creatorcontrib>Major, D</creatorcontrib><creatorcontrib>Newman, R.W</creatorcontrib><creatorcontrib>Dunleavy, U</creatorcontrib><creatorcontrib>Nicolson, C</creatorcontrib><creatorcontrib>Robertson, J.S</creatorcontrib><creatorcontrib>Schild, G.C</creatorcontrib><title>Preparation of vaccines against H5N1 influenza</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>In response to the pandemic warning provided by the highly pathogenic H5N1 influenza virus infections in Hong Kong, there were world-wide attempts to develop vaccines. 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Pre-clinical vaccine efficacy results are presented from one such strategy, that of using an apathogenic H5N3 avian strain for vaccine production.</description><subject>Animals</subject><subject>Baculoviridae - genetics</subject><subject>Humans</subject><subject>Influenza A (H5N1)</subject><subject>Influenza A virus - immunology</subject><subject>Influenza A Virus, H5N1 Subtype</subject><subject>Influenza Vaccines - immunology</subject><subject>Influenza virus</subject><subject>Mice</subject><subject>Vaccine</subject><subject>Vaccines, Attenuated - immunology</subject><subject>Vaccines, Synthetic - immunology</subject><subject>Virus</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1PGzEQhi3UiqSBn0C1p4oeFmb8sd49VQhBqRS1SIDEzfJ6x5VRshvsTaT219chEb2VnuYwz8yrmYexE4QzBKzO74BXspQIj6fAPwOgaEo8YFOstSi5wvodm74iE_YhpScAUAKbQzZBjpibesrObiOtbLRjGPpi8MXGOhd6SoX9aUOfxuJGfcci9H6xpv63PWLvvV0kOt7XGXu4vrq_vCnnP75-u7yYl05xOZa8oZbIKhBOOlc5Tl5qzVuvVMXBQcfrVnVtJzk0zlrvuRW5j1w0jUBPYsY-7fau4vC8pjSaZUiOFgvb07BORmPdoBbyTRBryWWd756x03-DCmpdASr9PyjoWub0jKod6uKQUiRvVjEsbfxlEMzWk3nxZLYSDHDz4slgnvu4j1i3S-r-Tu3FZODLDqD85U2gaJIL1DvqQiQ3mm4Ib0T8AddCn6o</recordid><startdate>20020515</startdate><enddate>20020515</enddate><creator>Wood, J.M</creator><creator>Major, D</creator><creator>Newman, R.W</creator><creator>Dunleavy, U</creator><creator>Nicolson, C</creator><creator>Robertson, J.S</creator><creator>Schild, G.C</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7T5</scope><scope>7U2</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20020515</creationdate><title>Preparation of vaccines against H5N1 influenza</title><author>Wood, J.M ; Major, D ; Newman, R.W ; Dunleavy, U ; Nicolson, C ; Robertson, J.S ; Schild, G.C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c524t-29ebeea503c4cc6c2ef4772bf55620c0d28b5dbd4209caaff2a37721239931fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Animals</topic><topic>Baculoviridae - genetics</topic><topic>Humans</topic><topic>Influenza A (H5N1)</topic><topic>Influenza A virus - immunology</topic><topic>Influenza A Virus, H5N1 Subtype</topic><topic>Influenza Vaccines - immunology</topic><topic>Influenza virus</topic><topic>Mice</topic><topic>Vaccine</topic><topic>Vaccines, Attenuated - immunology</topic><topic>Vaccines, Synthetic - immunology</topic><topic>Virus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wood, J.M</creatorcontrib><creatorcontrib>Major, D</creatorcontrib><creatorcontrib>Newman, R.W</creatorcontrib><creatorcontrib>Dunleavy, U</creatorcontrib><creatorcontrib>Nicolson, C</creatorcontrib><creatorcontrib>Robertson, J.S</creatorcontrib><creatorcontrib>Schild, G.C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Safety Science and Risk</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Vaccine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wood, J.M</au><au>Major, D</au><au>Newman, R.W</au><au>Dunleavy, U</au><au>Nicolson, C</au><au>Robertson, J.S</au><au>Schild, G.C</au><au>Kitler, ME</au><au>Lavanchy, D</au><au>Osterhaus, ADME</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preparation of vaccines against H5N1 influenza</atitle><jtitle>Vaccine</jtitle><addtitle>Vaccine</addtitle><date>2002-05-15</date><risdate>2002</risdate><volume>20</volume><spage>S84</spage><epage>S87</epage><pages>S84-S87</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><abstract>In response to the pandemic warning provided by the highly pathogenic H5N1 influenza virus infections in Hong Kong, there were world-wide attempts to develop vaccines. 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subjects | Animals Baculoviridae - genetics Humans Influenza A (H5N1) Influenza A virus - immunology Influenza A Virus, H5N1 Subtype Influenza Vaccines - immunology Influenza virus Mice Vaccine Vaccines, Attenuated - immunology Vaccines, Synthetic - immunology Virus |
title | Preparation of vaccines against H5N1 influenza |
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