Characterization of the anti-HIV effects of native lactoferrin and other milk proteins and protein-derived peptides

In a search for natural proteins with anti-HIV activity, we screened a large set of purified proteins from bovine milk and peptide fragments thereof. Because several charged proteins and peptides are known to inhibit the process of virus entry, we selected proteins with an unusual charge composition...

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Veröffentlicht in:	Antiviral research 2002-08, Vol.55 (2), p.341-355
Hauptverfasser:	Berkhout, Ben, van Wamel, Jeroen L.B., Beljaars, Leonie, Meijer, Dirk K.F., Visser, Servaas, Floris, René
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral activity Antiviral agents Antiviral Agents - pharmacology Biological and medical sciences CCR5 Receptor Antagonists Cell Line Electrostatic virus–cell interaction Genes, Viral HIV-1 - drug effects HIV-1 - physiology Humans Lactoferrin - pharmacology Medical sciences Milk protein Milk Proteins - pharmacology Peptide Fragments - pharmacology Pharmacology. Drug treatments Receptors, CXCR4 - antagonists & inhibitors Viral Envelope Proteins Virus Replication - drug effects
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