Endocannabinoids as physiological regulators of colonic propulsion in mice

Background & Aims: Activation of enteric cannabinoid CB1 receptors inhibits motility in the small intestine; however, it is not known whether endogenous cannabinoids (anandamide and 2-arachidonylglycerol) play a physiologic role in regulating intestinal motility. In the present study, we investi...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2002-07, Vol.123 (1), p.227-234
Hauptverfasser:	Pinto, Luisa, Izzo, Angelo A., Mascolo, Nicola, Capasso, Francesco, Cascio, Maria Grazia, Bisogno, Tiziana, Di Marzo, Vincenzo, Hospodar–Scott, Karen, Brown, David R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amidohydrolases - metabolism Animals Arachidonic Acids - pharmacology Biological and medical sciences Cannabinoid Receptor Modulators Cannabinoids - metabolism Colon - physiology Digestive system Endocannabinoids Ethanolamines Gastrointestinal Motility - drug effects Gastrointestinal Motility - physiology Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Mice Mice, Inbred ICR Palmitic Acids - metabolism Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Receptors, Cannabinoid Receptors, Drug - agonists Receptors, Drug - antagonists & inhibitors
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