A Soluble Isoform of the Rhesus Monkey Nonclassical MHC Class I Molecule Mamu-AG Is Expressed in the Placenta and the Testis

The nonclassical MHC class I locus HLA-G is expressed primarily in the placenta, although other sites of expression have been noted in normal and pathological situations. In addition, soluble HLA-G isoforms have been detected in the serum of pregnant and nonpregnant women as well as men. The rhesus...

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Veröffentlicht in:	The Journal of immunology (1950) 2002-07, Vol.169 (2), p.673-683
Hauptverfasser:	Ryan, Andy F, Grendell, Richard L, Geraghty, Daniel E, Golos, Thaddeus G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies, Monoclonal - metabolism Antigen-Antibody Reactions Base Sequence Blotting, Western Female Histocompatibility Antigens Class I - biosynthesis Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - immunology HLA Antigens - biosynthesis HLA Antigens - genetics HLA-G Antigens Humans Immunohistochemistry In Situ Hybridization Macaca mulatta Male Molecular Sequence Data Organ Specificity - genetics Organ Specificity - immunology Placenta - immunology Placenta - metabolism Protein Isoforms - biosynthesis Protein Isoforms - genetics Protein Isoforms - immunology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis Sequence Homology, Nucleic Acid Solubility Staining and Labeling Testis - immunology Testis - metabolism Transcription, Genetic - immunology
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