Human monocyte scavenger receptors are pattern recognition receptors for (1→3)-β-D-glucans

Glucans are cell wall constituents of fungi and bacteria that bind to pattern recognition receptors and modulate innate immunity, in part, by macrophage activation. We used surface plasmon resonance to examine the binding of glucans, differing in fine structure and charge density, to scavenger recep...

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Veröffentlicht in:Journal of leukocyte biology 2002-07, Vol.72 (1), p.140-146
Hauptverfasser: Rice, Peter J., Kelley, Jim L., Kogan, Grigorij, Ensley, Harry E., Kalbfleisch, John H., Browder, I. William, Williams, David L.
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Sprache:eng
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