From Genes to Therapy: The Case of Philadelphia Chromosome-Positive Leukemias

: The Philadelphia chromosome (Ph‐chromosome) has long represented the only cytogenetic abnormality known to be associated with a specific malignant disease in humans, being present in more than 95% of patients with chronic myelogenous leukemia. This abnormality is the result of a reciprocal translo...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2002-06, Vol.963 (1), p.306-312
Hauptverfasser:	CILLONI, DANIELA, GUERRASIO, ANGELO, GIUGLIANO, EMILIA, SCARAVAGLIO, PATRIZIA, VOLPE, GISELLA, REGE-CAMBRIN, GIOVANNA, SAGLIO, GIUSEPPE
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Transformation, Neoplastic - genetics Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy Philadelphia Chromosome Translocation, Genetic
Online-Zugang:	Volltext
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