Proteomic Strategies to Reveal Tumor Heterogeneity among Urothelial Papillomas

Proteomics and immunohistochemistry were used to reveal tumor heterogeneity among urothelial papillomas (UPs) with the long term goal of predicting their biological potential in terms of outcome. First, we identified proteins that were deregulated in invasive fresh lesions as compared with normal ur...

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Veröffentlicht in:	Molecular & cellular proteomics 2002-04, Vol.1 (4), p.269-279
Hauptverfasser:	Celis, Julio E, Celis, Pamela, Palsdottir, Hildur, Østergaard, Morten, Gromov, Pavel, Primdahl, Hanne, Ørntoft, Torben F, Wolf, Hans, Celis, Ariana, Gromova, Irina
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - metabolism Biomarkers, Tumor - metabolism Biopsy Blotting, Western Calgranulin B - biosynthesis Down-Regulation Electrophoresis, Gel, Two-Dimensional Fluorescent Antibody Technique, Indirect Heat-Shock Proteins - biosynthesis HSP30 Heat-Shock Proteins Humans Mass Spectrometry Membrane Proteins - biosynthesis Neoplasm Invasiveness Papilloma - diagnosis Papilloma - metabolism Phenotype Recurrence Time Factors Up-Regulation Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - metabolism Urothelium - metabolism Urothelium - pathology
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