Comparison of the Binding of Cadmium(II), Mercury(II), and Arsenic(III) to the de Novo Designed Peptides TRI L12C and TRI L16C

Designed α-helical peptides of the TRI family with a general sequence Ac-G(LKALEEK)4G-CONH2 were used as model systems for the study of metal−protein interactions. Variants containing cysteine residues in positions 12 (TRI L12C) and 16 (TRI L16C) were used for the metal binding studies. Cd(II) bindi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J.Am.Chem.Soc.124:8042,2002 2002, 2002-07, Vol.124 (27), p.8042-8054
Hauptverfasser: Matzapetakis, Manolis, Farrer, Brian T, Weng, Tsu-Chien, Hemmingsen, Lars, Penner-Hahn, James E, Pecoraro, Vincent L
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!