Impaired regulation of renal oxygen consumption in spontaneously hypertensive rats

Abnormalities of nitric oxide (NO) and oxygen radical synthesis and of oxygen consumption have been described in the spontaneously hypertensive rat (SHR) and may contribute to the pathogenesis of hypertension. NO plays a role in the regulation of renal oxygen consumption in normal kidney, so the res...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2002-07, Vol.13 (7), p.1788-1794
Hauptverfasser:	ADLER, Stephen, HUANG, Harer
Format:	Artikel
Sprache:	eng
Schlagworte:	Amlodipine - pharmacology Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Biological and medical sciences Bradykinin - pharmacology Cyclic N-Oxides - pharmacology Enalaprilat - pharmacology Free Radical Scavengers - pharmacology Hypertension - metabolism Investigative techniques of renal and urinary tract function Investigative techniques, diagnostic techniques (general aspects) Kidney - metabolism Kidney Cortex - metabolism Medical sciences Nitric Oxide Donors - pharmacology Oxygen Consumption - drug effects Rats Rats, Inbred SHR - metabolism Rats, Inbred WKY Reactive Oxygen Species - metabolism S-Nitroso-N-Acetylpenicillamine - pharmacology Spin Labels
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