Prediction of Survival in Diffuse Large-B-Cell Lymphoma Based on the Expression of Six Genes

The expression of 36 genes that have been linked to the outcomes in diffuse large-B-cell lymphoma was studied with the use of real-time polymerase chain reaction in biopsy specimens of the lymphoma. The pattern of expression of a group of 6 of the 36 genes correlated significantly with survival. The...

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Veröffentlicht in:	The New England journal of medicine 2004-04, Vol.350 (18), p.1828-1837
Hauptverfasser:	Lossos, Izidore S, Czerwinski, Debra K, Alizadeh, Ash A, Wechser, Mark A, Tibshirani, Rob, Botstein, David, Levy, Ronald
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Analysis of Variance Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Cells Clinical trials DNA polymerase Female Gene Expression Gene Expression Profiling General aspects Genes Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma Lymphoma, B-Cell - drug therapy Lymphoma, B-Cell - genetics Lymphoma, B-Cell - mortality Lymphoma, Large B-Cell, Diffuse - drug therapy Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - mortality Male Medical sciences Medical treatment Middle Aged Models, Genetic Models, Statistical Multivariate Analysis Oligonucleotide Array Sequence Analysis Prognosis Reverse Transcriptase Polymerase Chain Reaction Survival Analysis
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