Modulation of Multidrug Resistance and Apoptosis of Cancer Cells by Selected Carotenoids

The multidrug resistance (MDR) proteins that belong to the ATP-binding casette superfamily are present in a majority of human tumors and are an important final cause of therapeutic failure. Therefore, compounds which inhibit the function of the MDR-efflux proteins may improve the cytotoxic action of...

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Veröffentlicht in:	In vivo (Athens) 2004-03, Vol.18 (2), p.237-244
Hauptverfasser:	Molnár, Joseph, Gyémánt, Nóra, Mucsi, Ilona, Molnár, Annamária, Szabó, Margaret, Körtvélyesi, Tamás, Varga, András, Molnár, Péter, Tóth, Gyula
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Capsicum - chemistry Carotenoids - chemistry Carotenoids - pharmacology Cell Line, Tumor Drug Resistance, Multiple - drug effects Drug Resistance, Multiple - genetics Genes, MDR Humans Mice Neoplasms - drug therapy Neoplasms - genetics Neoplasms - metabolism Plant Extracts - chemistry Plant Extracts - pharmacology Rhodamine 123 - metabolism Transfection
Online-Zugang:	Volltext
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