Assessing Protein Patterns in Disease Using Imaging Mass Spectrometry

Direct tissue profiling and imaging mass spectrometry (MS) provides a detailed assessment of the complex protein pattern within a tissue sample. MALDI MS analysis of thin tissue sections results in over of 500 individual protein signals in the mass range of 2 to 70 kDa that directly correlate with p...

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Veröffentlicht in:	Journal of proteome research 2004-03, Vol.3 (2), p.245-252
Hauptverfasser:	Chaurand, Pierre, Schwartz, Sarah A, Caprioli, Richard M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Neoplasms - metabolism Carcinoma, Non-Small-Cell Lung - metabolism Glioma - metabolism Humans Lung Neoplasms - metabolism Mass Spectrometry - methods Mice Neoplasms - metabolism Peptides - chemistry Prognosis Proteins - chemistry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Time Factors
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