Autocrine Ligands for the Epidermal Growth Factor Receptor Mediate Interleukin-8 Release from Bronchial Epithelial Cells in Response to Cigarette Smoke

Airway neutrophilia is a prominent feature of chronic obstructive pulmonary disease. As cigarette smoke (CS) and epidermal growth factor (EGF) both cause release of interleukin-8 (IL-8) from epithelial cells in vitro, we investigated whether autocrine ligands for the EGF receptor (EGFR) are involved...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of respiratory cell and molecular biology 2002-07, Vol.27 (1), p.85-90
Hauptverfasser:	Richter, Audrey, O'Donnell, Rory A, Powell, Robert M, Sanders, Michael W, Holgate, Stephen T, Djukanovic', Ratko, Davies, Donna E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amphiregulin Bronchi - cytology Bronchi - metabolism Cell Survival - drug effects Cell Survival - physiology Cells, Cultured EGF Family of Proteins Epidermal Growth Factor - genetics Epidermal Growth Factor - metabolism ErbB Receptors - metabolism Glycoproteins - genetics Glycoproteins - metabolism Growth Substances - genetics Growth Substances - metabolism Heparin-binding EGF-like Growth Factor Humans Intercellular Signaling Peptides and Proteins Interleukin-8 - genetics Interleukin-8 - metabolism Middle Aged Nicotiana - adverse effects Respiratory Mucosa - metabolism Smoking - metabolism Transforming Growth Factor alpha - genetics Transforming Growth Factor alpha - metabolism Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!