Risk factors for acute graft-versus-host disease in patients undergoing transplantation with CD34+ selected blood cells from HLA-identical siblings

A study on 315 patients undergoing transplantation with CD34+ selected blood cells from HLA-identical siblings was performed to determine risk factors for acute GVHD (aGVHD). Recipients of a dose of CD34+ cells (× 106/kg) of 2 or less, more than 2 to 4, and more than 4 had a cumulative incidence of...

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Veröffentlicht in:	Blood 2002-07, Vol.100 (2), p.724-727
Hauptverfasser:	Urbano-Ispizua, Alvaro, Rozman, Ciril, Pimentel, Pedro, Solano, Carlos, de la Rubia, Javier, Brunet, Salut, Pérez-Oteyza, Jaime, Ferrá, Christelle, Zuazu, Javier, Caballero, Dolores, Bargay, Joan, Carvalhais, Alzira, Dı́ez, Jose Luis, Espigado, Ildefonso, Alegre, Adrián, Rovira, Montserrat, Campilho, Fernando, Odriozola, Jesús, Sanz, Miguel Angel, Sierra, Jordi, Garcı́a-Conde, Javier, Montserrat, Emili
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Adult Age Factors Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigens, CD34 - analysis Biological and medical sciences Blood Cells - immunology Blood Cells - transplantation Bone marrow, stem cells transplantation. Graft versus host reaction CD3 Complex - analysis Female Graft vs Host Disease - etiology Hematologic Neoplasms - complications Hematologic Neoplasms - therapy Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - methods Histocompatibility Testing Humans Incidence Male Medical sciences Middle Aged Nuclear Family Risk Factors Sex Factors Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation, Isogeneic - adverse effects Transplantation, Isogeneic - methods
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