Modulation by hyperpolarization-activated cationic currents of voltage responses in human rods

We used the whole-cell patch-clamp recording technique on surgically excised human retina to examine whether human rod photoreceptors express hyperpolarization-activated cationic currents ( I h) and to analyze the effects of I h on rod’s voltage responses. Hyperpolarizing voltage steps from a holdin...

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Veröffentlicht in:	Brain research 2002-07, Vol.943 (1), p.48-55
Hauptverfasser:	Kawai, Fusao, Horiguchi, Masayuki, Suzuki, Hiromitsu, Miyachi, Ei-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Cyclic Nucleotide-Gated Cation Channels Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Humans Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Inner segment Ion Channels - physiology Kinetics Membrane Potentials - physiology Middle Aged Nerve Tissue Proteins - physiology Patch-clamp Patch-Clamp Techniques - methods Potassium Channels Retinal cell Retinal detachment Retinal Rod Photoreceptor Cells - physiology Rod Vertebrates: nervous system and sense organs
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