Blunted Prefrontal Cortical 18Fluorodeoxyglucose Positron Emission Tomography Response to Meta-Chlorophenylpiperazine in Impulsive Aggression

BACKGROUND Impulsive aggression is a prevalent problem and yet little is known about its neurobiology. Preclinical and human studies suggest that the orbital frontal cortex and anterior cingulate cortex play an inhibitory role in the regulation of aggression. METHODS Using positron emission tomograp...

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Veröffentlicht in:	Archives of general psychiatry 2002-07, Vol.59 (7), p.621-629
Hauptverfasser:	New, Antonia S, Hazlett, Erin A, Buchsbaum, Monte S, Goodman, Marianne, Reynolds, Diedre, Mitropoulou, Vivian, Sprung, Larry, Shaw, Robert B, Koenigsberg, Harold, Platholi, Jimcy, Silverman, Jeremy, Siever, Larry J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Aggression - drug effects Aggression - psychology Biological and medical sciences Fluorodeoxyglucose F18 Functional Laterality - drug effects Functional Laterality - physiology Glucose - metabolism Gyrus Cinguli - diagnostic imaging Gyrus Cinguli - drug effects Gyrus Cinguli - metabolism Humans Impulsive Behavior - metabolism Impulsive Behavior - psychology Medical sciences Piperazines - pharmacology Prefrontal Cortex - diagnostic imaging Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Serotonin Receptor Agonists - pharmacology Social behavior disorders. Criminal behavior. Delinquency Tomography, Emission-Computed - statistics & numerical data
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