Putting out the fire: what terminates calcium-induced calcium release in cardiac muscle?

The majority of contractile calcium in cardiac muscle is released from stores in the sarcoplasmic reticulum (SR), by a process of calcium-induced calcium release (CICR) through ryanodine receptors. Because CICR is intrinsically self-reinforcing, the stability of and graded regulation of cardiac EC c...

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Veröffentlicht in:	Cell calcium (Edinburgh) 2004-06, Vol.35 (6), p.591-601
Hauptverfasser:	Stern, Michael D, Cheng, Heping
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Cardiac muscle Ion Channel Gating - physiology Myocardial Contraction - physiology Myocardium - metabolism Ryanodine receptor Ryanodine Receptor Calcium Release Channel - metabolism Sarcoplasmic reticulum
Online-Zugang:	Volltext
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